This year’s list goes to the Atlantic City Sands project, a mega-casino the size of Las Vegas that was approved last year and is currently under construction. The hotel, which will open by the end of the year, will be one of the largest in the world.
The next largest is the MGM Grand in MGM Park, New Jersey, where it will have a gaming floor the size of one-third of New Jersey’s entire population.
So, what’s the biggest gambling property on the planet?
It comes back to Las Vegas. The Sands project alone boasts a massive gambling floor of 1.9 million square feet. The second place goes to the MGM Grand in MGM Park, New Jersey which has a gaming floor the size of a small village.
In the past few years, research in biology and genetics has suggested that obesity and diabetes are linked.
A new study by Harvard researchers suggests a genetic link between obesity and diabetes may be even more pervasive than previously thought with some people with a genetic variant known as COMT2.
The analysis finds that for overweight people, obesity and their family members are more likely to carry a variant in COMT2 gene that reduces the activity of the enzyme that converts glucose into fat – a gene that some studies have linked to the severity of both obesity and diabetes.
“It has all the makings of an interesting finding,” said David Ludwig, a professor of genome sciences and co-director of the Harvard Genome Center.
In this article, we explain the genetic component of obesity and how COMT2 is likely the biggest factor in this equation.
COMT Is One Factor
COMT stands for cytochrome oxidase – a molecule produced by cells that helps them metabolize fats. COMT2 is the most common single-nucleotide polymorphism (SNP) in the genetic code, and more than 200,000 copies of the variant, called the COMT gene, have been identified in humans. The disease that COMT2 is responsible for, type 2 diabetes, affects about 10,000 to 15,000 Americans.
There are six major COMT2 variants used to study what factors are necessary for obesity and diabetes:
2,3-diaphorase mutation, which can cause a “typical” gene knockout (i.e., you have the gene knockout itself)
excess or low levels (hyperglycemia or hypergly